Lupus Science & Medicine: 11 (Suppl 2) (2024)

Lupus Science & Medicine: 11 (Suppl 2) (1)

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2024 - Volume 11 - Suppl 2

Lupus 21st Century 2023 Abstracts, September 27–30, Naples, Florida

Abstracts

  • 101 Lupus nephritis mortality by sex, age, geographic region, urbanization, and race/ethnicity: a nationwide population-based study (16 May, 2024)

    Ram Raj Singh, Snehin Rajkumar, Eric Yen

  • 102 Rheumatology-based social determinants of health screening to uncover and address needs (16 May, 2024)

    Candace H Feldman, Rebecca Summit, Karli Retzel, Haelynn Gim, Leah Santacroce, Shalina Patel, Sarah Wilke, Virginia Bills, Siobhan Case, Caitlyn Wasserman, Derrick Todd, Nancy Shadick, Sara Schoenfeld

  • 103 A novel, community-engaged approach to encourage diverse patient participation in lupus clinical trials (16 May, 2024)

    Saira Z Sheikh, Tessa Englund, Andrew Simkus, Nicole Wanty, Annie McNeill, Kristen Holtz, Tenesha Hood, Starla Blanks, Maria Allen, Allen Anandarajah

  • 105 Non-traditional risk factors predict cardiovascular disease and contribute to disparities in a population-based cohort with systemic lupus erythematosus (16 May, 2024)

    S Sam Lim, Jessica Williams, Gaobin Bao, Tené Lewis, Charmayne Dunlop-Thomas, Cristina Drenkard

  • 106 Adapting the lupus conversations program for rheumatology nurses: increasing clinical trial knowledge to promote diversity in lupus clinical trials (16 May, 2024)

    Khadija Dantata, Lauren Topf, Stephanie Slan, Melicent Miller, Rosalind Ramsey Goldman, Rodlescia Sneed, Candace H Feldman, Tori Justin, Lydia Oberholtzer, Joy Buie

  • 107 Clinician-led intervention to improve medication adherence among patients with SLE (16 May, 2024)

    Kai Sun, Nneka Molokwu, Emily Hanlen-Rosado, Amy Corneli, Kathryn Pollak, Jennifer Rogers, Rebecca Sadun, Lisa Criscione-Schreiber, Jayanth Doss, Hayden Bosworth, Megan Clowse

  • 201 IL-4 acts through aryl hydrocarbon receptor to antagonize TLR7-induced double negative 2 B cells in lupus (16 May, 2024)

    Changming Lu, Hui-Chen Hsu, Jose Rubio, W Winn Chatham, John D Mountz

  • 202 Investigating the role of interferon in promoting flares of SLE at a single cell level (16 May, 2024)

    Zoha Faheem, Giselle M Boukhaled, Kieran Manion, Carolina Munoz-Grajales, Carol Nassar, Mickael Kim, Dafna Gladman, Murray Urowitz, Zahi Touma, David Brooks, Joan Wither

  • 203 Follicular B cell derived CD21lo B cells are immediate precursors to autoreactive extrafollicular ASCs (16 May, 2024)

    D Zhu, K Oleinika, A Rattan, M Carroll

  • 204 ZEB2 acts as a crucial transcriptional regulator governing age- associated B cell formation and pathogenicity in systemic lupus erythematosus (16 May, 2024)

    Dai Dai, Shuangshuang Gu, Xiaxia Han, Huihua Ding, Yang Jiang, Sheng Chen, Nan Shen

  • 205 Local tissue microenvironment regulates T cell phenotypes in murine systemic lupus erythematosus (16 May, 2024)

    Smita Shuchi, Mark Shlomchik, Minjung Kim, Jeremy Tilstra

  • 206 T cells and tissue injury in lupus (16 May, 2024)

    Joseph Craft

  • 301 Treatment of systemic lupus erythematosus patients with upadacitinib results in the coordinated inhibition of type 1 IFN-related biomarkers: biomarker analysis of the M19–130 (SLEek) phase 2 study (16 May, 2024)

    Marie-Claude Gaudreau, James Fann, Shalina Contrepois, Alan Friedman, Thierry Sornasse, Joan T Merrill

  • 302 Resting state functional connectivity in SLE patients and association with cognitive impairment and blood-brain barrier permeability (16 May, 2024)

    John G Hanly, Jason W Robertson, Alexandra Legge, Lyna Kamintsky, Guillermo Aristi, Alon Friedman, Steven D Beyea, John D Fisk, Antonina Omisade, Cynthia Calkin, Tim Bardouille, Chris Bowen, Kara Matheson, Javeria A Hashmi

  • 303 Clinical and laboratory associations of longitudinal cell-bound complement activation products in SLE (16 May, 2024)

    Jennifer L Rogers, Amanda M Eudy, Daniel Wojdyla, Tyler O’Malley, David S Pisetsky, Lisa G Criscione-Schreiber, Kai Sun, Rebecca E Sadun, Mithu Maheswaranathan, Jayanth Doss, Roberta Vezza Alexander, Megan EB Clowse

  • 304 Dysregulated serum cytokines in association with clinical manifestations in patients with systemic lupus erythematosus (16 May, 2024)

    Loqmane Seridi, Stephen Leonardo, Brittney Scott, Robert M Gordon, Cathye Shu, Kaiyin Fei, Kim Hung Lo, Anne Stevens, Sheng Gao

  • 305 Using ACR-component based unsupervised clustering with Olink proteomics to resolve SLE heterogeneity (16 May, 2024)

    Eugene Myshkin, Steven Leonardo, Anne Stevens, Loqmane Seridi, Matthew J Loza, Dawn Waterworth

  • 306 Persistence of urinary biomarkers of intrarenal inflammation precedes loss of kidney function in lupus nephritis (16 May, 2024)

    Andrea Fava, Mohammed G Atta, Jose Monroy Trujillo, Derek Fine, Daniel Goldman, Peter Izmirly, H Michael Belmont, the Accelerating Medicines Partnership in RA/SLE, Jill Buyon, Michelle Petri

  • 307 The quest for biomarkers in cutaneous lupus erythematosus (16 May, 2024)

    Benjamin F Chong

  • 308 Transcriptional profiles associated with pericarditis in patients with systemic lupus erythematosus (SLE) identify purine metabolism pathway genes as candidate mediators (16 May, 2024)

    Olferiev Mikhail, Drogy Madison, Fernandez David, A Kirou Kyriakos, K Crow Mary

  • 309 Serum markers of disease activity correlate with pain perception in systemic lupus erythematosus patients (16 May, 2024)

    Kei-Lwun Yee, Lihong Huo, Graziela Perri, Lindsy Forbess, Swamy Venuturupalli, Mariko Ishimori, Daniel J Wallace, Caroline Jefferies

  • 310 ELUCIDATE-Epigenetics; lupus urine cells in decoding APOL1 transmutation effect (16 May, 2024)

    Ashira D Blazer, Olusola Ayanlowo, William Liao, Ida Dzifa Dey, Jasmin Divers, Uyi Ima-Edomwonyin, Hakeem Olasoebikan, Cristina Lanata, Girish Nadkarni, Jill Buyon, Peter Izmirly, Timothy Niewold

  • 401 Single-cell RNA sequencing reveals cellular drivers of UV-mediated skin injury in cutaneous lupus (16 May, 2024)

    Mitra P Maz, Feiyang Ma, Mehrnaz Gharaee-Kermani, Amanda M Victory, Amy Hurst, Johann Gudjonsson, J Michelle Kahlenberg

  • 402 Study design and rationale for the efficacy and safety assessment of daxdilimab, a selective plasmacytoid dendritic cell depleter, in a phase 2 trial of patients with moderate-to-severe primary discoid lupus erythematosus (16 May, 2024)

    Adina K Knight, David Larson, Liangwei Wang, Linda Zhu

  • 403 Trends in incidence and prevalence of atherosclerotic cardiovascular disease among patients with cutaneous lupus erythematosus from 2018–2020 (16 May, 2024)

    Henry W Chen, Jialiang Liu, Donghan Yang, Yang Xie, Eric Peterson, Ann Marie Navar, Benjamin F Chong

  • 404 The interferon-rich skin environment regulates Langerhans cell ADAM17 to promote photosensitivity in lupus (16 May, 2024)

    Thomas M Li, Pamela Zuckerman, Victoria Zyulina, Ethan S Seltzer, Marija Dacic, Yurii Chinenov, Andrea R Daamen, Keila R Veiga, Noa Schwartz, David J Oliver, Jose Lora, Ali Jabbari, Yong Liu, William D Shipman, William G Ambler, Sarah F Taber, Karen B Onel, Jonathan H Zippin, Mehdi Rashighi, James G Krueger, Niroshana Anandasabapathy, Inez Rogatsky, Carl P Blobel, Peter E Lipsky, Theresa T Lu

  • 501 Association between ultra-processed food intake with risk of systemic lupus erythematosus in women (16 May, 2024)

    Sinara Laurini Rossato, Chun-Han Lo, Medha Barbhaiya, Jeffrey A Sparks, Neha Khandpur, Susan Malspeis, Kazuki Yoshida, Walter C Willett, Karen H Costenbader

  • 502 The epigenetics of the now known 330 lupus genetic risk loci in two ancestries are independently consonant with causal regulatory mechanisms involving epstein-barr virus (EBV)-encoded transcription co-factors expressed in EBV-infected, EBV latency III-expressing B cells (LCLs) (16 May, 2024)

    Viktoryia Laurynenka, Xiaoting Chen, Sreeja Parameswaran, Leah C Kottyan, Matthew T Weirauch, Iouri Chepelev, Kenneth M Kaufman, John B Harley

  • 503 Intestinal permeability correlates with disease activity and DNA methylation changes in lupus patients (16 May, 2024)

    Mckenna M Bowes, Desiré Casares-Marfil, Amr H Sawalha

  • 504 Hair chemical use and systemic lupus erythematosus: a case-control study (16 May, 2024)

    Jessica A English, Trevor D Faith, Dulaney A Wilson, Jim C Oates, Gary S Gilkeson, Diane L Kamen

  • 601 Racial/Ethnic and regional differences by place of death in lupus nephritis (16 May, 2024)

    Snehin Rajkumar, Ram Raj Singh

  • 602 The role of active nephritis, compared to active non-renal SLE, in pregnancy outcomes (16 May, 2024)

    Megan EB Clowse, Amanda Eudy

  • 603 Trajectories of antimalarial adherence among newly diagnosed rheumatoid arthritis and systemic lupus erythematosus patients: a population-based cohort study (16 May, 2024)

    J Antonio Avina-Zubieta, M Rashedul Hoque, Diane Lacaille, Mary ADe Vera, Yi Qian, Lawrence McCandless, Hui Xie, John M Esdaile

  • 604 Identification of ACR guidelines for SLE pregnancy care in the electronic health record (16 May, 2024)

    Noah Forrest, Joshua Waytz, April Barnado, Megan Clowse, Theresa Walunas, Rosalind Ramsey-Goldman

  • (16 May, 2024)

    Amanda M Eudy, Jennifer L Rogers, Daniel Wojdyla, Kai Sun, Rebecca Sadun, Mithu Maheswaranathan, Jayanth Doss, Lisa Criscione-Schreiber, Megan EB Clowse

  • 606 Visualizing lupus through clinical data-driven Butterflies (16 May, 2024)

    Sandrine Huot, Paul R Fortin, Anne-Sophie Julien, Alexandra Godbout, Nathalie Amiable, Cynthia Laflamme, Marc Pouliot

  • 607 Differences in social support among African American Women with and without systemic lupus erythematosus (SLE) (16 May, 2024)

    Sarah Smith, Chloe Mattila, L Quinnette King, Lori Ann Ueberroth, Edith M Williams, Diane L Kamen, Bethany J Wolf, Paula S Ramos

  • 608 Utility 2019 EULAR/ACR SLE criteria to re-classify patients with interstitial pneumonia with autoimmune features as SLE with interstitial lung disease (16 May, 2024)

    Gabriela Martinez-Zayas, Elena Kopeikin Joerns, David R Karp

  • 609 Pregnancy outcomes in systemic lupus erythematosus (SLE): data from a multiethnic, multinational Latin American cohort (16 May, 2024)

    Rosa Maria Serrano Morales, Romina Nieto, Rosana Quintana, Paula Alba, Sabrina Porta, Lucia Hernández, Guillermo Berbotto, Verónica Inés Bellomio, Nílzio Da Silva, Odirlei Monticielo, Fernando Cavalcanti, Francinne Machado Ribeiro, Eduardo Borba, Eloisa Bonfa, Loreto Massardo, Gustavo Aroca Martínez, Andrés Cadena Bonfanti, Gerardo Quintana Lopez, Mario Javier Moreno Alvarez, Jorge Antonio Esquivel Valerio, Isabel Acosta-Colman, Astrid Paats, Claudia Mora, Marina Scolnik, Diana Fernández Ávila, Carmen Funes Soaje, Veronica Saurit, Mercedes García, Eduardo Kerzberg, Graciela Gomez, Cecilia Pisoni, Edgard Reis Neto, Iris Guerra Herrera, Oscar Neira, Carlos Cañas, Miguel A Saavedra, Margarita Portela, Hilda Fragoso Loyo, Luis Humberto Silveira Torre, Ignacio Garcia-De La Torre, Manuel F Ugarte-Gil, Armando Calvo Quiroz, Roberto Muñoz Louis, Ricardo Robaina, Vicente Juarez, Alvaro Danza, Carlos Enrique Toro Gutierrez, Carlos Abud-Mendoza, Ana Malvar, Graciela S Alarcon, Ashley Orillion, Urbano Sbarigia, Anne Stevens, Federico Zazzetti, Guillermo Pons-Estel, Bernardo Pons-Estel

  • 610 Predictors of first hospitalizations due to disease activity and infections in systemic lupus erythematosus patients (16 May, 2024)

    Rosana Quintana, Romina Nieto, Rosa Serrano Morales, Manuel F Ugarte-Gil, Guillermina B Harvey, Daniel Wojdyla, Jose A Gómez-Puerta, Mercedes García, Luis Catoggio, Veronica Saurit, Cristina Drenkard, Nílzio Da Silva, Fernando Cavalcanti, Eduardo Borba, Emília Sato, Oscar Neira, Loreto Massardo, Gloria Vásquez, Luis Alonso González, Marlene Guibert-Toledano, Luis Humberto Silveira Torre, Ignacio Garcia-De La Torre, Maria Josefina Sauza DEL Pozo, Rosa Chacon, Graciela S Alarcon, Ashley Orillion, Urbano Sbarigia, Federico Zazzetti, Bernardo Pons-Estel, Guillermo Pons-Estel

  • 611 Advancing data harmonization in a federated model/network for assessing patient characteristics in systemic lupus erythematosus (16 May, 2024)

    Michel van Speybroeck, Teresa A Simon, Martine Lewi, Reyhan Sonmez, Enkeleida Nikai, Chureen Carter, Urbano Sbarigia, Federico Zazzetti, Frederic Lavie, Chetan S Karyekar

  • 612 Racial and ethnic disparities in patients with incomplete lupus erythematosus (16 May, 2024)

    Peri Newman, Jamie Carter, Duanping Liao, Diane Kamen, Judith James, Cristina Arriens, David Karp, Nancy Olsen

  • 615 Employment trajectory of Canadian young adults with systemic lupus erythematosus (16 May, 2024)

    Lily SH Lim, Menelaos Konstanidis, Zahi Touma, Diane Lacaille, Umut Oguzoglu, Christine Peschken, Nicole Anderson, Ramandeep Kaur, Eleanor Pullenayegum

  • 616 Comparison of optical and ultrasound imaging in lupus arthritis (16 May, 2024)

    Wei Tang, Alessandro Marone, Leila Khalili, Xin Wang, Shane Murray, Sean Inzerillo, Moegammad Bardien, Vedant Gaikwad, Stephen Kim, Laura Geraldino-Pardilla, Andreas Hielscher, Anca Askanase

  • 617 Doing everything possible to prioritize work: lived work experience of young adults with systemic lupus erythematosus (16 May, 2024)

    Michael A Golding, Fareha Nishat, Kaitlyn A Merrill, Ramandeep Kaur, Jennifer Stinson, Jennifer LP Protudjer, Roberta L Woodgate, Christine Peschken, Diane Lacaille, Umut Oguzoglo, Zahi Touma, Lily SH Lim

  • 618 Lived educational experience of young adults with childhood- and adult-onset systemic lupus erythematosus: a multi-center Canadian qualitative study (16 May, 2024)

    Michael A Golding, Fareha Nishat, Kaitlyn A Merrill, Ramandeep Kaur, Jennifer Stinson, Jennifer LP Protudjer, Roberta L Woodgate, Christine Peschken, Diane Lacaille, Umut Oguzoglo, Zahi Touma, Lily SH Lim

  • 619 Pregnancy outcomes among patients with lupus and their relatives: a population based cohort study (16 May, 2024)

    Jessica A English, Katie Kirchoff, Diane L Kamen

  • 620 Clinical management of lupus in the United States: a claims-based analysis (16 May, 2024)

    Kathryn M Kingsmore, John Zent, Peter E Lipsky

  • 621 Risk of damage progression with belimumab versus oral immunosuppressant use in patients with systemic lupus erythematosus (16 May, 2024)

    April Jorge, Baijun Zhou, Yuqing Zhang, Hyon Choi

  • 622 Performance characteristics of systemic lupus erythematosus and lupus nephritis electronic phenotype algorithms among medicare patients in a well-defined South Carolina cohort (16 May, 2024)

    Jeffrey R Curtis, Jim C Oates

  • (16 May, 2024)

    Dennis H Clark, Isaac TW Harley, Celi Sun, Iouri Chepelev, R Hal Scofield, Kenneth M Kaufman, John B Harley, Viktoryia Laurynenka

  • 702 Comparative genome wide association studies (GWASs) of systemic lupus erythematosus (SLE) and multiple sclerosis (MS) from the million veteran program (MVP) (16 May, 2024)

    Viktoryia Laurynenka, Dennis H Clark, Celi Sun, R Hal Scofield, Kenneth M Kaufman, Isaac TW Harley, John B Harley, Iouri Chepelev

  • 703 Pervasive sharing of causal genetic risk factors contributes to clinical and molecular overlap between Sjögren’s Disease and SLE (16 May, 2024)

    Karen Chau, Yanint Raksadawan, Kristen Allison, John A Ice, R Hal Scofield, Iouri Chepelev, Isaac TW Harley

  • 704 Global identification of lupus genetic risk variants modulating the type I interferon pathway through CRISPR-based genomic screening (16 May, 2024)

    Guojun Hou, Xinyi Zhu, Yutong Zhang, Zhaorui Cheng, Nan Shen

  • 705 Examination of the shared genetic architecture between multiple sclerosis and systemic lupus erythematosus facilitates discovery of novel lupus risk loci (16 May, 2024)

    Sophia Kerns, Katherine A Owen, Amrie C Grammer, Peter E Lipsky

  • 405 VISTA, a novel regulator of type I interferon production in the skin (16 May, 2024)

    Zachary Peters, Lindsay Mendyka, Sicong Shan, Dorothea Barton, Christopher Burns, Randolph Noelle, Sladjana Skopelja-Gardner

  • 406 Unraveling the mystery of SLE: a look at MHC-II alleles (16 May, 2024)

    Suparna Kumar, Theresa T Lu

  • 801 Overexpression of human TLR8 induces bone marrow dysfunction and severe anemia in lupus- prone mice (16 May, 2024)

    Naomi I Maria, Julien Papoin, Chirag Raparia, Zeguo Sun, Rachel Josselsohn, Ailing Lu, Hani Katerji, Mahrukh M Syeda, David Polsky, Robert Paulson, Theodosia Kalfa, Betsy J Barnes, Weijia Zhang, Lionel Blanc, Anne Davidson

  • 802 UV light causes dendritic cell migration and differentiation of a unique Type I IFN-I dependent dendritic cell to draining lymph nodes (16 May, 2024)

    Xizhang Sun, Jaime Chao, Michael Gerner, Keith B Elkon

  • 803 Bacterial biofilms activate human innate immune cells (16 May, 2024)

    Leah Whiteman, Brian Le, Kaitlyn Grando, Lauren K Nicastro, Roberto Caricchio, Çagla Tükel, Stefania Gallucci

  • 804 Genetic dissection of TLR9 reveals complex regulatory and cryptic pro-inflammatory roles in murine lupus (16 May, 2024)

    Claire Leibler, Shinu John, Rebecca A Elsner, Kayla B Thomas, Shuchi Smita, Stephen Joachim, Russell C Levack, Derrick Callahan, Rachael Gordon, Sheldon Bastacky, Ryutaro f*ckui, Kensuke Miyake, Sebastien Gingras, Kevin M Nickerson, Mark J Shlomchik

  • 901 Cross-sectional analysis of lupus erythematosus and dermatomyositis stress and cardiovascular health (LEADS-CV) data reveals ideal cardiovascular health is rare in affected youth (16 May, 2024)

    Kaveh Ardalan, Angel Davalos, Hwanhee Hong, Bryce B Reeve, Christoph P Hornik, M Anthony Moody, Donald Lloyd-Jones, Eveline Y Wu, Audrey Ward, Rebecca Sadun, Jeffrey Dvergsten, Ann M Reed, Mark Connelly, Laura E Schanberg

  • 902 Effect of cumulative hydroxychloroquine dose on prevention of damage progression and major adverse cardiovascular events in patients with systemic lupus erythematosus (16 May, 2024)

    Jordan Jacquez, Sam Good, Lisa Zhu, Manpreet Singh, Caroline Siegel, Lori Sahakian, Brian Skaggs, Jennifer Grossman, Maureen McMahon

  • 903 Cardiovascular risk management in cutaneous and cutaneous with systemic lupus erythematosus (16 May, 2024)

    Megan Zhao, Rui Feng, Kevin Jon Williams, Victoria P Werth

  • 904 Left ventricular dysfunction and inflammatory markers in systemic lupus erythematosus (SLE) patients with and without coronary microvascular dysfunction (16 May, 2024)

    Audrey M Hagiwara, Moumita Bose, Marianne Bernardo, Michael D Nelson, Janet Wei, Daniel S Berman, Mariko Ishimori, C Noel Bairey Merz, Daniel Wallace, Caroline Jefferies

  • 1001 East Asian lupus nephritis in the hopkins lupus cohort (16 May, 2024)

    Michelle Petri, Chenglong Fang, Daniel W Goldman

  • 1002 Single cell transcriptomics in kidney tissue from African American patients enrolled in the accelerating medicines partnership (AMP) implicates tubular cells in the pathogenesis of APOL1 associated lupus nephritis (16 May, 2024)

    Philip M Carlucci, Jasmine Shwetar, Siddarth Gurajala, Qian Xiao, Joseph Mears, Katie Preisinger, Devyn Zaminski, Kristina Deonaraine, Peter Izmirly, Andrea Fava, Judith A James, Joel Guthridge, Brad Rovin, Sethu Madhavan, Wade DeJager, David Wofsy, Ming Wu, Chaim Putterman, Deepak Rao, Betty Diamond, Derek Fine, Jose Monroy-Trujillo, Kristin Haag, H Michael Belmont, William Apruzzese, Anne Davidson, Fernanda Payan-Schober, Richard Furie, Paul Hoover, Celine C Berthier, Maria Dall’Era, Kerry Cho, Diane Kamen, Kenneth Kalunian, Jennifer Anolik, Arnon Arazi, Soumya Raychaudhuri, Nir Hacohen, Michelle Petri, Robert Clancy, Kelly Ruggles, Jill Buyon

  • 1003 Longitudinal gut microbiome analyses and blooms of pathogenic strains during lupus disease flares (16 May, 2024)

    Gregg J Silverman, Peter Izmirly, Jill Buyon, Alexander V Alekseyenko Doua F Azzouz

  • 1004 C3d-imaging in lupus nephritis (16 May, 2024)

    Joshua M Thurman, Felix Poppelaars, V Michael Holers

  • 1005 Response gene to complement-32 facilitates local recruitment of Th1 and Th17 cells and promotes renal inflammation in immune complex mediated glomerulonephritis (16 May, 2024)

    Vinh Nguyen, Alexandru Tatomir, John Papadimitriou, Cinthia Drachenberg, Tudor Badea, Horea Rus, Violeta Rus

  • 1006 Evaluation of intra-renal plasmacytoid dendritic cells in active lupus nephritis (16 May, 2024)

    Brad H Rovin, Samir V Parikh, Su Jing Chan, Luke Jandreski, Kyle Ferber, Catherine Barbey, Taylor L Reynolds

  • 1007 Voclosporin for lupus nephritis: assessment of long-term safety and efficacy including renal outcome over three years of treatment in the phase 3 AURORA 1 and AURORA 2 studies (16 May, 2024)

    Samir V Parikh, Cristina Arriens, Lucy Hodge, Christopher M Mela, Henry Leher

  • 1009 In-depth analysis of myeloid cell subsets in lupus nephritis kidneys provides insights into disease mechanisms: lessons from the accelerating medicines partnership (AMP) in RA/SLE consortium (16 May, 2024)

    Arnon Arazi, Paul J Hoover, Thomas M Eisenhaure, Siddarth Gurajala, Qian Xiao, Joseph Mears, Deepak A Rao, Celine C Berthier, Andrea Fava, Michael Peters, Tony Jones, Saori Sakaue, William Apruzzese, Jennifer L Barnas, Derek Fine, James Lederer, Richard Furie, David A Hildeman, Steve Woodle, Judith A James, Joel M Guthridge, Maria Dall’Era, David Wofsy, Peter M Izmirly, H Michael Belmont, Robert Clancy, Diane L Kamen, Chaim Putterman, Thomas Tuschl, Maureen A McMahon, Jennifer Grossman, Kenneth C Kalunian, Fernanda Payan-Schober, Mariko Ishimori, Michael Weisman, Matthias Kretzler, Jeffery Hodgin, Michael B Brenner, Jennifer H Anolik, Michelle A Petri, Jill P Buyon, Soumya Raychaudhuri, Betty Diamond, Nir Hacohen, Anne Davidson, the Accelerating Medicines Partnership (AMP) RA/SLE Network

  • 1010 Development of a scoring system for accurate lupus nephritis case identification from real-world databases (16 May, 2024)

    Zara Izadi, Alfredo Aguirre, Christine Anastasiou, Julia Kay, Gabriela Schmajuk, Jinoos Yazdany

  • 1011 Degranulating PR3+ myeloid cells characterize proliferative lupus nephritis (16 May, 2024)

    Alessandra Ida Celia, Xiaoping Yang, Michelle Petri, Avi Rosenberg, Andrea Fava

  • 1012 Deep peripheral blood immunophenotyping identifies a subgroup of lupus nephritis patients characterized by high type 1 interferon signaling, persistent activated immune cells and poor renal response to standard of care at 1 year (16 May, 2024)

    Alice Horisberger, Alec Griffith, Arnon Arazi, Joshua Keegan, Kaitlyn Howard, Takanori Sasaki, Tusharkanti Ghosh, Andrea Fava, Rebecca Beuschel, Jun Inamo, John Pulford, Ekaterina Murzin, Brandon Hanco*ck, Katie Preisinger, Maria Gutierrez-Arcelus, Thomas M Eisenhaure, Joel Guthridge, Paul J Hoover, Maria Dall’Era, David Wofsy, Diane L Kamen, Kenneth C Kalunian, Richard Furie, Michael Belmont, Peter Izmirly, Robert Clancy, David Hildeman, Steve Woodle, William Apruzzese, Maureen A McMahon, Jennifer Grossman, Jennifer L Barnas, Fernanda Payan-Schober, Mariko Ishimori, Michael Weisman, Matthias Kretzler, Celine C Berthier, Jeffrey Hodgin, Chaim Putterman, Nir Hacohen, Michael B Brenner, Jennifer H Anolik, Anne Davidson, Judith A James, Soumya Raychaudhuri, Michelle A Petri, Jill P Buyon, Betty Diamond, the Accelerating Medicines Partnership (AMP) RA/SLE Network, Fan Zhang, James A Lederer, Deepak A Rao

  • 1013 The role of mitochondrial calcium uniporter (MCU) in lupus (16 May, 2024)

    Xinyan Zhang, Ryan J Pachucki, Chelsea Corradetti, John Elrod, Stefania Gallucci, Roberto Caricchio

  • 1014 Calcineurin inhibitors for treatment of lupus nephritis: a systematic review and meta-analysis of randomized controlled trials (16 May, 2024)

    Gabriel Figueroa-Parra, Maria C Cuellar-Gutierrez, Mariana González-Treviño, Larry J Prokop, M Hassan Murad, Alí Duarte-García

  • 1015 Discovery and validation of anti-Formin-like 1 autoantibodies in Lupus nephritis (16 May, 2024)

    Marco Prunotto, ZEUS consortium, GianMarco Ghiggeri

  • 1101 Lysosome dysfunction and the accumulation of immune complexes associates with active disease in human systemic lupus erythematosus (16 May, 2024)

    Barbara Vilen, SunAh Kang, Liubov Arbeeva, Shruti Saxena-Beem, Anthony Trujillo, Karissa Grier, Megan EB Clowse, Saira Z Sheikh, Jennifer L Rogers

  • 1102 Low C-reactive protein (CRP) levels in SLE are explained by increased interleukin-6 (IL- 6) receptor shedding under interferon-α and IL-6 (16 May, 2024)

    Martyna Hempel, Erik Klapproth, Babett Heschel, Nicolai Leuchten, Ali El-Amouche, Martin Aringer

  • 1103 Dosage length of 2-deoxyglucose treatment has organ-specific transcriptome effects in a lupus-prone mouse model (16 May, 2024)

    Ann E Wells, John J Wilson, Sarah E Heuer, Jian Wei, Colleen Mayberry, Derry C Roopenian, Chih-Hao Chang, Gregory W Carter

  • 1104 Machine learning to determine the endotype of SLE patients: a validation study (16 May, 2024)

    Erika L Hubbard, Prathyusha Bachali, Kathryn M Kingsmore, Amrie C Grammer, Peter E Lipsky

  • 1105 Persistent neuroinflammation in SLE (16 May, 2024)

    Bruce Volpe, Kaitlin Carroll, Mark Mizrachi, Meggan Mackay, An Vo, David Eidelberg, Pina Sanelli, Cynthia Aranow, Betty Diamond

  • 1106 An historical perspective on SLE pathogenesis (from my entry into the field until now) (16 May, 2024)

    Betty Diamond

  • 1201 SGLT2 inhibitors modulate inflammation and germinal centers in lupus (16 May, 2024)

    Javier Rangel-Moreno, Maria de la Luz Garcia-Hernandez, Mary O’Connell, Daria Krenitsky, Maria Fernanda Ossa-Echeverri, Mark Lusco, John Looney, Jennifer H Anolik

  • 1202 Unveiling metabolic vulnerabilities in lupus B cells: targeting BCMA and glucose dependency for therapeutic strategies (16 May, 2024)

    John J Wilson, Jian Wei, Andrea R Daamen, Colleen L Mayberry, Amrie C Grammer, Peter E Lipsky, Derry C Roopenian, Chih-Hao Chang

  • 1301 Factors driving disparities in glucocorticoid exposure among children with SLE in the CARRA registry (16 May, 2024)

    William Daniel Soulsby, Rebecca Olveda, Jie He, Laura Berbert, Edie Weller, Laura Schanberg, Emily von Scheven, Aimee Hersh, Mary Beth F Son, Joyce C Chang, Andrea M Knight, on behalf of the CARRA Registry Investigators

  • 1302 Fetal cardiac and neonatal dermal fibroblast phenotypes and cytokine reactivity following macrophage crosstalk in the pathogenesis of neonatal lupus (16 May, 2024)

    Christina Firl, Robert Clancy, Jill Buyon

  • 1303 Physician global assessment of disease activity in childhood-onset systemic lupus erythematosus – Does the approach matter? (16 May, 2024)

    Ekemini A Ogbu, Hermine I Brunner, Jennifer L Huggins, Angela Merritt, Megan Quinlan-Waters, Catherine Robben, Chen Chen, Daniel J Lovell, Bin Huang

  • 1304 CARRA-PReS consensus recommendations for patient reported outcome measures in childhood-onset systemic lupus erythematosus registries (16 May, 2024)

    JC Cooper, EM Smith, LB Lewandowski, RE Sadun

  • 1305 Implementing a treat to target strategy for lupus in the pediatric rheumatology clinic: baseline implementation assessment (16 May, 2024)

    Emily A Smitherman, Julia G Harris, Aimee O Hersh, Jennifer L Huggins, Livie Timmerman, Jon M Burnham

  • 1306 Neuropsychiatric manifestations in childhood-onset systemic lupus erythematosus: association with N-Methyl-D- aspartate receptor NR2 subunit and cytokines (16 May, 2024)

    Samara Rosa Sepresse, Ana Carolina Londe Capelli Alencar, Jaqueline Cristina de Amorim, Taís Nitsch Mazzola, Mariana Moraes da Silva Lucino, Roberto Marini, Simone Appenzeller

  • 1401 Autophagy due to altered lipid homeostasis precipitates diffuse alveolar hemorrhage (DAH) in murine lupus (16 May, 2024)

    Shuhong Han, Haoyang Zhuang, Westley H Reeves

  • 1402 Embracing a biopsychosocial approach to type 2 SLE: insights from the type 2 SLE consortium (16 May, 2024)

    Jennifer L Rogers, Megan EB Clowse, Amanda M Eudy

  • 1403 Loneliness among individuals living with inflammatory rheumatic diseases during the later stages of the COVID-19 pandemic (16 May, 2024)

    D Da Costa, N Andersen, E McGuire, E Rollet-Labelle, JG Hanly, C Hitchon, J-B Deville-Stoetzel, L Bessette, M-C Audet, S Lagacé, C Grondin, P Desaulniers, PR Fortin

  • 1501 Long-term safety of belimumab among adult patients with systemic lupus erythematosus (SLE): pooled data from three open-label extension studies over 11+ years (16 May, 2024)

    Aneela N Mian, Paula Curtis, Christine Henning, Munther Khamashta, Ricard Cervera, Daniel J Wallace, Maria G Tektonidou, Tatsuya Atsumi

  • 1502 Lupus low disease activity state attainment in the phase 3 placebo-controlled TULIP long-term extension trial of anifrolumab (16 May, 2024)

    Eric F Morand, Ronald van Vollenhoven, Richard A Furie, Kenneth C Kalunian, Sule Yavuz, Gabriel Abreu, Catharina Lindholm, Hussein Al-Mossawi

Issue Information

  • Table of Contents (PDF)
  • Editorial Board (PDF)
Lupus Science & Medicine: 11 (Suppl 2) (2024)
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